Aspartame intolerance

Aspartame Intolerance There are claims that aspartame is responsible for a range of disorders, from depression to multiple sclerosis to death. These theories are chemically untenable. The molecule is immediately hydrolyzed in the intestine to its components, aspartic acid, phenylalanine, and methanol, and does not enter the bloodstream. 

Because of the high incidence of lactose intolerance in the general population, lactose is not recommended as a sweetener for pediatric populations [70]. Aspartame, a phenylalanine derivative, is incorporated in many chewable tablets and sugar-free dosage forms. Aspartame-containing products should be avoided in children with autosomal recessive phenylketonuria [54]. 

The food industry is a fertile area for biocatalysis applications high-fructose corn syrup (HFCS) from glucose with glucose isomerase, the thermolysin-catalyzed synthesis of the artificial sweetener Aspartame , hydrolysis of lactose for lactose-intolerant consumers, and the synthesis of the nutraceutical i-camitine in a two-enzyme system from "ybutyrobetaine all serve as examples. 

Children are especially vulnerable to the toxic effects of aspartame probably because formaldehyde is totally intolerable to biological systems. 

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