Asparagine, glutamate dehydrogenase

Fig. 1.3 Reactions showing synthesis of glutamate in brain. Aspartate aminotransferase (1) glu-taminase (2) glutamate dehydrogenase (3) GABA aminotransferase (4) alanine aminotransferase (5) ornithine aminotransferase (6) Al-pyrroline 5-carboxylic acid dehydrogenase (7) and asparagine synthetase (8)...

Ammonium ions are produced by the catabolism of a number of amino acids. Glutamate dehydrogenase is the major source of ammonium ions in the body. Ammonium ions are also produced from the catabolic pathways of serine, histidine, tryptophan, glycine, glutamine, and asparagine. L-Amino acid oxidase and... 

Fig. I. Metabolic map for synthesis and metabolism of glutamate and aspartate. AAT = aspartate aminotransferase AS = asparagine synthetase GAD = glutamic acid decarboxylase GDH = glutamate dehydrogenase GS = glutamine synthetase OAT = ornithine D-aminotransferase P5CDH = l-pyrroline-5-carboxylate dehydrogena.se PAG = phosphate-activated glutaminase PO = proline oxidase TCA = tricarboxylic acid.

Fig. 2. The incorporation of ammonia derived by a number of pathways, into asparagine in higher plants, a. Nitrate reductase b, nitrite reductase c, nitrogenase .d, glutamine synthetase e, asparagine synthetase f, arginase g, urease h, ornithine transaminase i, glutamate dehydrogenase j, proline dehydrogenase k, transaminases.

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