As antifungal agent

Two closely related pyridotriazines have been described as antifungal agents. Displacement of halogen on nitro-... 

PS(180)1909>, or from its derived Schiff base (Equation 81) <2004JHC281> the same is true of the examples 264-266 in Scheme 64 <2000FA109>. The latter have been tested as antifungal agents. 

MR, Mortierella ramannianus PC, Penicillium chrysogenum are used as antifungal agents. 

Carotenoid catabolic products also have a physiological role in the plant. Oxidative cleavage of carotenoids by carotenoid cleavage dioxygenases (CCDs) generates apocarotenoids [21]. Apocarotenoids serve the plant as antifungal agents or in the synthesis of flavor or aroma of flowers and fruits. A well-known downstream product of an apocarotenoid is abscisic acid (ABA), a phytohormone in plants [21]. 

The complex polyene macrolide antibiotics are clinically effective as antifungal agents. Scott Rychnovsky of the University of California at Irvine has reported (Angew. Chem. hit. Ed. 2004,43, 2822) the first synthesis of rimocidinolide methyl ester 4, the aglycone of rimocidin 1. The key step in the synthesis is the condensation of the aldehyde 2 with the phosphonate 3, leading to 4. 

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