Arthralgia paclitaxel

Paclitaxel Infection, nausea, vomiting, diarrhea, mucositis, arthralgia, Mild (day 1 only)... [Pg.1330]

Paclitaxel -natural taxane inhibits depolymerization of tubulin in mitotic spindle apparatus -bone marrow suppression -nausea and vomiting—mild -mucocutaneous effects (mucositis, stomatitis, diarrhea) -hypersensitivity reactions -peripheral neuropathy -myalgias, arthralgias -mild vesicant... [Pg.177]

The severity of myalgia and arthralgia correlated significantly with the total cumulative dose of paclitaxel 210 mg/m /cycle by 3-hour infusion in 247 patients with a median cumulative dose of 630 mg/m (47). [Pg.2666]

Neurotoxicity may be severe enough to require discontinuation treat myalgias/arthralgias with NSAIDs, narcotic analgesics In paclitaxel-cisplatin combination regimens, give paclitaxel first to decrease neutropenia... [Pg.2301]

Musculoskeletal Arthralgia and/or myalgia have been reported in 20-30% of patients receiving paclitaxel they typically occur... [Pg.941]

Musculoskeletal Docetaxel is associated with arthralgias and myalgias, usually starting 1-2 days after infusion and lasting up to 5 days [142 ]. As with paclitaxel, gaba-pentin given prophylactically controls symptoms in some patients [69 ]. [Pg.947]

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