Arterial hypertension, angina pectoris, myocardial infarction

Arterial hypertension, angina pectoris, myocardial infarction 

Hypertension and coronary heart disease (CHD) are of great importance. Hypertension affects above 20% of the total population of the USA with its major impact on those over age 50. CHD is the cause of death in 30% of males and 22% of females in England and Wales. Management requires attention to detail, both clinical and pharmacological. 

The way drugs act in these diseases is outlined and the drugs are described according to class. 

Dilatation can be achieved through direct relaxation of vascular smooth muscle cells, by stimulation of nitric oxide (NO) production, or by blocking (suppressing) endogenous vasconstrictors, noradrenaline (norepinephrine) and angiotensin. 

Modem antihypertensive drugs lower blood pressure with minimal interference with homeostatic control, i.e. change in posture, exercise. 

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It is used for stable and nonstable angina pectoris (including after myocardial infarctions) as well as in arterial hypertension. Universally accepted synonyms of this dmg are cardizem, dilacor, tiazac, iproventaril, and others. 

The root of Salvia miltiorrhiza has been used as Chinese folk medicine for the treatment of cardiovascular diseases, such as ischemia, angina pectoris, coronary heart disease, myocardial infarction, and hypertension. Many studies on the secondary metabolites from Salvia miltiorrhiza revealed that tanshinones were a group of compounds responsible for these biological activities, especially for the treatment of coronary artery disease and h5 rtension. 

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