Artemisia apiacea

China Artemisia apiacea Hance ex Walpers Dihydroartemisinin, artesunate, artemisinin, chloroquine.33 This herb is mildly toxic. A schizonticidal agent, antimalarial. 

Apart from A. annua, qinghaosu (1) was detected in only one other Artemisia species Artemisia apiacea But the abundance was too low (0.08%) to justify an isolation on a technical scale. 

For malarial diseases, add Herba Artemisiae Apiaceae (QingHao) and Radix Dichroae Febrifugae (Chang Shan). 

For concomitant yin vacuity, add Carapax Amydae (Bie Jia) and Herba Artemisiae Apiaceae QingHao). 

Representative formula Qing Hao Bie Jia Tang (Artemisia Apiacea Carapax Amydae Decoction) Composition ... 

Herba Artemisiae Apiaceae QingHao), 6g Carapax Amydae Bie Jia), 15g raw Radix Rehmanniae Xi Sheng Di), 12g Rhizoma Anemarrhenae Zhi Mu), 6g Cortex Radicis Moutan Dan Pi), 9g... 

Asteraceae, Milliaceae and Apiaceae, are among some plant families that are known to have insecticidal constituents. Vulgar-one B (isolated from Artemisia douglasiana Asteraceae), apiol (isolated from Ligusticum hultenii Apiaceae), and cnicin (isolated from Centaurea maculosa Asteraceae) cause significant mortality to Formosan subterranean... 

The other major group of irregular monoterpenes is formed by non-head-to-tail fusion of isoprene units. Important members include artemisia ketone 64, santolinatriene 65, chrysanthemol 66, yomogi alcohol 67 and lavandulol 68 (Structure 4.15). Lavandulane-type compounds occur in the families Lamiaceae (Labiatae) and Apiaceae (Umbelliferae), while chrysanthemane, artemisane and santolinane types occur in the family Asteraceae (Compositae) [47,48]. 

Artemisia annua L. A. apiacea Hance ex Walpers Qing Guo (Stinking artemisia) (aerial part) Dihydroartemisinin, artesunate, artemisinin, chloroquine, flavonoids, sesquiterpene.33-269-476 This herb is mildly toxic. A schizonticidal agent, antimalarial, treat infections of multidrug-resistant strains of Plasmodium falciparum, the cause of human malignant cerebral malaria. 

U. utillis, Viburnum sargenti Gardenia angusta, G. jasminoides Euphorbia hirta Artemisia annua, A. apiacea... 

Sesquiterpene Alpinia officinarum, Artemisia annua, A. apiacea, Curcuma longa, Cyperus rotundus, Dryobalanops aromatica, D. camphora, Ginkgo biloba, Hedychium coronarium, Jasminum samba, Melaleuca leucadendra, Nardostachys jatamansi, Xanthoxylum piperitum... 

Apigenin (= 5,7,4 -Trihydroxyflavone) (flavone) Apiuni, Daucus (Apiaceae), Achillea, Artemisia (Asteraceae), Mentha, Thymus (Lamiaceae) spp. ferns Aminopeptidase N (42% inhibition at 300 pM) [63]... 

Daucus (Apiaceae), Betula (Betulaceae), Artemisia, Baccharis (Asteraceae), Ribes (Grossulariaceae), Juglans (Juglandaceae) spp., glycoside in Prunus puddum (Rosace ae) Semi-synthetic from Kaempferol... 

Propenylanisole anisum (aniseed) (Apiaceae), Artemisia [carminative,... 

Umbelliferone (= Dichrin A Hydrangin 7-Hydroxycoumarin Skimmetin) (coumarin) Terpene Artemisia capillari (Asteraceae), Ammi majus, Apium, Ferula, Heracleum, Pimpinella spp. (Apiaceae), Aegk marmelos, Citrus grandis (Rutaceae), Hydrangea paniculata (Saxifragaceae), Atropa belladonna (Solanaceae) [root] AR (bovine lens) (30) 14.5t... 

A number of monoterpenes do not fit the isoprene mle and are called irregular monoterpenes. There are three major stmctural types of irregular monoterpenes the chrysan-themyl (89), artemisyl (90), and santolinyl (91) skeletons (Charlwood and Banthorpe, 1978 Charlwood and Chari-wood, 1991a). These compounds are found primarily in the Asteraceae (they are especially well known from the genus Artemisia), although a few are found in the Apiaceae and Lamiaceae (Poulter, 1990). As two skeletal types often occur in the same plant, it is reasonable to suspect that a common biosynthetic pathway exists and it is possible that the three types arise from a common cationic species (Fig. 19.21). 

Fig. 98.2 Guaianolides isolated from plants belonging to Asteraceae (3-8, 12) and Apiaceae (9-12). Compound 3 matricin fmm Matricaria chamomilla [2], 4 mpicolin A 8-0-acetate from Artemisia tripartita [2], 5 from Lasiolaena morii [9], 6 from Artemisia xanthochroa [10], 7 bacchariolide from Baccharis salicina [11], 8 cichopumolide from Cichorium pumilum [12], 9 from Hymenoxys scaposa var. villosa [13], 10 from Laser trilobum [14], 11 thapsigargin from Thapsia garganica [15], and 12 carmenin fromFerula sp. (Apiaceae) [16, 17] and from Artemisia lanata (Asteraceae) [18]...

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