Arrhythmogenic effects of Ox-LDL

It is evident that we presently have a good understanding of the biochemical and biophysical changes that accompany oxidative modification of LDL, and many interesting biological properties of oxidised LDL have been identified. 

Nevertheless, the summary of the proceedings [137] of a National Heart, Lung, and Blood Institute workshop September 5-6, 1991, Bethesda, MD, entitled Antioxidants in the prevention of human atherosclerosis will serve as a conclusion More Basic Research is needed on the mechanisms involved in the oxidative modification of LDL and on the ways in which various antioxidants influence it and More animal studies are needed to establish firmly that protection of LDL against oxidative modification does influence the progression of lesions . 

Chemical aspects of free radical reactions in connective tissue 

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