Arrested flow systems

CASE III IGNITION < ) NEAR ARRESTER FIGURE 5-13. Effect of ignition source location—flowing system. 

The Penumbra stroke system (Penumbra Inc., San Leandro, CA) includes two different revascularization options (1) thrombus debulking and aspiration may be achieved by a reperfusion catheter that aspirates the clot while a separator device fragments it, and (2) direct thrombus extraction may be performed by a ring retriever while a balloon guide catheter is used to temporarily arrest flow. This system has been tested in a pilot trial in Europe. Twenty patients (mean NIHSS 21) with a total of 21 vessel occlusions (7 ICA, 5 MCA, and 9 Basilar) were treated up to 8 hours after symptom onset. Recanalization prior to lA lysis was achieved in all cases (48% TIMI 2 52% TIMI 3). Seven patients were also treated with lA UK or rt-PA. Good outcome at 30 days (defined as mRS < 2 or NIHSS 4-point improvement) was demonstrated in 42%. The mortality rate was 45%, but there were no device-related deaths. There was one asymptomatic SAH and three symptomatic ICHs. A prospective, single-arm, multicenter trial is being conducted in the United States and Europe currently. 

One flow system that has been designed to minimise the effects of relaxation and is commonly used in infrared chemiluminescence studies is designated the arrested relaxation system [77]. Figure 2 shows an... 

Elame Arrester A flame arrester is a device permeable to gas flow but impermeable to any flame. It quenches the flame and cools the products sufficiently to prevent reignition at arrester outlet. Arresters are used to prevent a flame propagating into the system from outside (such as via a tank vent) or one part of the system to another (such as through connected piping). 

The flame propagation direction affects the type of flame arrester selected. An end-of-line or in-line deflagration flame arrester used for the protection of an individual tank may be of a unidirectional design because the flame will only propagate from the atmosphere towards the tank interior. A bidirectional flame arrester design, however, is needed for an in-line application in a vapor recovery (vent manifold) system because the vapors must be able to flow from the tank interior into the manifold, or from the manifold into the tank interior. Consequently, flame may propagate in either direction. 

Consideration shonld also be given to the possibility that the flame arrester may ping, which conld prodnce a vacnnm condition in a low-pressnre tank when the tank is primped out, and implode (collapse) the tank. This may reqnire the installation of a vacnnm breaker or a pressnre-vacnnm conservation valve. If the tank contents are flammable and admission of air may resnlt in an ignitable mixture, it may be necessary to install an inert gas blanketing system on the tank, actuated by a pressnre controller, which would admit a sufficient flow of inerting gas when a vacnnm condition is detected. 

An interlock system (sensors and valves) which isolates offgas flow to die process heater firebox and routes the offgas to atmosphere on detection of low nitrogen flow or high temperature at the detonation flame arrester outlet. 

Flame Arrester A device fitted to the opening of an enclosure or to the connecting piping of a system of enclosures and whose intended function is to allow flow but prevent the transmission of flame from either a deflagration or detonation. 

Vasopressin is a potent vasoconstrictor that increases blood pressure and systemic vascular resistance. It may have several advantages over epinephrine. First, the metabolic acidosis that frequently accompanies cardiopulmonary arrest can blunt the vasoconstrictive effect of epinephrine this does not occur with vasopressin. Second, stimulation of P receptors by epinephrine can increase myocardial oxygen demand and complicate the postresuscitative phase of CPR. Vasopressin can also have a beneficial effect on renal blood flow in the kidney, causing vasodilation and increased water reabsorption. 

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