5- aroyl

Simple aziridines are optically transparent in the UV region of the electromagnetic spectrum (B-69MI50401). In more highly substituted aziridines, such as the 2-aroyl-3-arylaziridines (9), there is an interaction between the carbonyl and aryl ring substituents... 

Benzimidazole, 2-amino-5-bromo-l-methyl-diazo coupling, 5, 429 Benzimidazole, 2-amino-6-bromo-1 -methyl-diazo coupling, 5, 429 Benzimidazole, 2-amino-1-ethyl-alkylation, 5, 438 Benzimidazole, 2-amino-1-methyl-acylation, 5, 438 bromination, 5, 429 tautomerism, 5, 368 Benzimidazole, 4-amino-2-methyl-diazo coupling, 5, 429 Benzimidazole, 2-aroyl-mass spectra, 5, 360 Benzimidazole, 1-aryl-metallation, 5, 448 reactions... 

Imidazole, 2-amino-1 -methyl-4,5-diphenyl-tautomerism, 5, 368 Imidazole, 2-aroyl-mass spectra, 5, 360 synthesis, 5, 391, 402 UV spectra, 5, 356 Imidazole, 4-aroyl-synthesis, 5, 474 Imidazole, C-aroyl-UV spectra, 5, 356 Imidazole, aryl-nitration, 5, 396, 433 oxidation, 5, 433 Imidazole, 1-aryl-dipole moments, 5, 351 dearylation, 5, 449 ethylation, 5, 448 H NMR, 5, 353 hydroxymethylation, 5, 404 rearrangement, 5, 108 synthesis, 5, 390 thermal rearrangement, 5, 363 Imidazole, 2-aryl-chlorosulfonation, 5, 397 synthesis, 5, 475 Imidazole, 4-aryl-bromination, 5, 399 Imidazole, C-aryl-electrophilic substitution, 5, 432-433 nitration, 5, 433 Imidazole, N-aryl-reactions, 5, 448-449 structure, 5, 448-449 Imidazole, arylmercapto-... 

R = OCHg, R = N(CHg)2] on treatment with polyphosphoric acid give the corresponding 2-aroyl-l-oxo-l,2,3,4-tetrahydro-j8-carboline (177). In the latter instance the use of acetic anhydride... 

Six-membered heterocycles with one tellurium and two nitrogen atoms in the ring are represented by 2-aroyl derivatives of 1,2,3-telluradiazine and 5,6-benzo-1,2,3-telluradiazine 89. For the synthesis of these compounds, IV-aroylhydrazones of 2-bromotellurenylcyclohexenealdehyde and 2-bromotellurenylbenzaldehyde 90 were used as the starting materials (98ZOK959). Dehydrobromination of the hydrazones 90 occurs on treatment with triethylamine and gives the heterocycles 89 in about 80% yields. 

Aroyl-pyridine werden mit Titan(III)-chlorid/Lithiumalanat mit bis zu 93% d.Th. zu den entsprechenden Alkoholen reduziert. Als Nebenprodukt fallen dimere Verbindungen an z.B.5 ... 

Treatment of 2-aroyl-3-aminoacrylates 442, or their 0-acetate derivatives <1996USP5539110> with KF, or with another base, yielded 7-oxo-2,3-dihydro-7f/-pyrido[l,2,3- i ]-l,4-benzoxazine-6-carboxylates or 6-carboxylic acids (e.g., <1996GEP4428020, 1997H(45)137>). Cyclization of 2-aroyl-3-aminoacrylates 443 <1997H(45)137> or their O-acetates <1996USP5539110> led to pyrido[l,2,3- i ]-l,4-benzoxazine-6-carboxylic acids 444 (Equation 84). 

Microwave irradiation in solvent-free conditions induces the cleavage of the 2,3-bond of 2-aroyl-aziridines 135 to give an azomethine ylide intermediate, which subsequently undergoes cycloadditions to a multiple bond and leads to oxazolidine, imidazoline, naphthooxazole and pyrroline derivatives 136 in good yields (Scheme 9.41) [32b], Reactions were performed at atmospheric pressure in an Erlenmeyer flask placed in a commercial domestic oven. The reactions were complete in 10-15 min while the conventional method requires 18-20 h. 

Bowden and Taylor (1971b) have made a comprehensive survey of intramolcular catalysis of this type in the alkaline hydrolysis of 2-aroyl and... 

A facile three step process, under mild conditions, for the synthesis of 2,4-diarylfurans with the same or different substituents on the two aryl rings, starting from benzaldehydes and acetophenones, employing Haller-Bauer type cleavage of 2-aroyl-33-diarythirans was described <99S61>. 

Die thermische Zersetzung von 2-Aryl-l-azido-2-oxo-ethanen in Diphenylether bei 180-240= fiihrt zu 2-Aroyl-4-aryl-imidazolen (46-84%)229. Analoge Produkte werden auch bei der thermischen Zersetzung von 1,1-Dimethyl-1-(2-oxo-2-phenyl-ethyl)-hydrazinium-Salzen erhal-ten230,231. Bei beiden Reaktionen werden die entsprechenden a-Imino-ketone als Zwischen-produkte angenommen. 

Kohlcnsaure-(2-aroyl-hydrazid)-dialkylamide Man lost 0,03 mol Aroyl-hydrazin in 15 ml Pyridin untcr schwachem Erwarmen und fugt dann 0,033 mol N,N-Dialkyl-carbamidsaure-chlorid hinzu. Nach 12 h Stehen fallt man mit Wasscr die Semicarbazide aus, wiischt mil Wasser und trocknet. 

Hydroxy-l, 3,4-oxadiazole Das Kohlensaure-(2-aroyl-hydrazid)-dialkylamid wird in DMF einige h bis zur Beendigung der Dialkylamin-Entwicklung zum Sieden erhitzt und das Endprodukt mit Wasser ausgefallt. 

Die Cyclisierung wurde bei Kohlensaure-(2-aroyl-hydrazid)-dimethylamiden in 1,2-Dichlor-benzol bei 160 170° (45 min) auch in Gegenwart von Chlorwasserstoff erreicht423. 

Eine interessante Variante der oxidativen Cyclisierung von 2-Aroyl-hydrazonen ist die Reaktion mit Schwefel, die aufier 1,3,4-Thiadiazolen (vgl. S. 235) in Abhangigkeit von den Substiluenten und Reaktionsbedingungen in guten Ausbeuten 1,3,4-Oxadiazole liefert494 ... 

By means of oxidation of the initially formed 3,4-disubstituted 5-bromo-2-bromomethylpyrrole, bromine converted 3,4-disubstituted-2-methylpyr-roles and their 5-carboxylic acids into 5-bromo-5 -bromomethyl-2,2 -dipyrrolylmethanes. Similar reaction with sulfuryl chloride led to the analogous chloro species (77MI2). Whereas treatment of 2-aroyl-l,3-dimethylpyrrole-5-acetic esters with NBS brominated the vacant ring carbon, the related oxalate ester gave the 3-bromomethyl derivative (80JMC98). 

Pyrazolo[4,3-b]pyridine 181 (R1 = H,R2 = Me) in refluxing pyridine was acylated and tosylated in the 1-position. Milder conditions afforded either a 2-acyl or a mixture of 1- and 2-aroyl derivatives, suggesting a possible equilibrium between the two products.111... 

The use of complex aromatic a-haloketones affords special 2-aroyl-benzofurans, such as 263 (condensation of salicylaldehyde with 2-bromoacetylthianthrene)634 and 264 (condensation of salicylaldehyde with 2-bromoacetylbenzofuran).399... 

Aroyl Benzopurans from Salicylic Aldehydes and Aromatic Haloketones... 

Cyano,687 2-dimethylcarboxamido-,688,689 2-acetyl-,543 and 2-aroyl-687,690 3(2f/)benzofuranones (285) have been obtained from the corresponding esters (284) by a similar method. 

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