Arginine pyroglutamate

Synonyms Arginine pyroglutamate L-Arginine-L-pyroglutamate 5-Oxo-L-proline, compd. with L-arginine (1 1) L-Proline, 5-oxo-, compd. with L-arginine (1 1)... 

L-Glutamine [56-85-9] M 146.2, m 184-185", [alp +31.8" (M HCl). Likely impurities are glutamic acid, ammonium pyroglutamate, tyrosine, asparagine, isoglutamine, arginine. Crystd from water. 

Serum AKI Healthy subjects 1 7 patients 1 7 LC-MS Acylcarnitines, methionine, homocysteine, pyroglutamate, ADMA, phenylalanine, arginine, and lysophosphatidylcholines (51)... 

Oxidation of proline and arginine residues leads also to formation of glutamate semialdehyde and, upon its further oxidation, to pyroglutamic acid (A9). Oxidized proline produces also 2-pyrrolidone (K6) (Fig. 5). 

Likely impurities are glutamic acid, ammonium pyroglutamate, tyrosine, asparagine, isoglutamine, arginine. Crystd from water. 

The vimcidal activity of monopercitric acid (MPCA) was determined by suspension tests against both nonenveloped and enveloped viruses including VACV [120], The study showed that vimses were 99.9% inactivated by a 0.5% concentration within 30 s demonstrating MPCA as a suitable candidate for a disinfectant. Sugimoto and Toyoshima [107] reported on the inactivation of VACV by N -Cocoyl-L-Arginine Ethyl Ester, DL-Pyroglutamic Acid Salt after a 30 min exposure at room temperature. At all tested concentrations (0.025%, 0.05%, 0.1%, and 0.25%), there was greater than 90% inactivation of VACV. 

Sugimoto, Y., and Toyoshima, S., 1997. Na-cocoyl-L-arginine ethyl ester, DL-pyroglutamic acid salt, as an inactivator of hepatitis B surface antigen. Antimicrob. Agents Chemother., 16 329—332. 

Figure 2.1 The amino acid sequence of a h5rpothalamic peptide neurotensin. The three-letter codes stand for the following amino acids ARG (arginine), ASN (asparagine), GLU (glutamic acid), ILE (isoleucine), LEU (leucine), LYS (lysine), PRO (proline), PYG (pyroglutamic acid), and TYR (t5trosine). (Data from Garraway, R. and Leeman, S.E., /. Biol. Chem., 250, 1907, 1975. With permission.)...

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