Arabidopsis thcdiana

More complex shikimate derivatives have also been produced. One example is the antioxidant, anti-inflammatory, and antiproliferative hydroxycinnamoyl anthranilates (also known as avenanthramides or Avns). The production was first shown from feeding of cinnamates and anthranilates, but the entire pathway from glucose was also demonstrated by using feedback-resistant AroG and TyrA as well as exogenous 4-coumarate CoA ligase from Arabidopsis thcdiana and hydroxycinnamoyl/benzoyl-CoA/anthranilate Af-hydroxycinnamoyl/ benzoyltransferase from Dianthus caryophyllus (carnation) [43]. 

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