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Aprepitant Emend

Aprepitant (Emend) 125 mg on day 1, 1 hour prior to Most common Fatigue, hiccups... [Pg.300]

Aprepitant (Emend) [Centrally Acting Antiemetic] Uses Pre-vents N/V assoc w/ emetogenic CA chemo (eg, cisplatin) (use in combo w/ other antiemetics) Action Substance P/neurokinin l(NKi) receptor antagonist Dose 125 mg PO day 1, 1 h before chemo, then 80 mg PO qAM days 2 3 Caution [B, /-] Contra Use w/ pimozide, Disp Caps SE Fatigue, asthenia, hiccups Interactions T Effects W/ clarithromycin, diltiazem, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, troleandomycin T effects OF alprazolam, astem-izole, cisapride, dexamethasone, methylprednisolone, midazolam, pimozide, terfe-nadine, triazolam, chemo agents, eg, docetaxel, etoposide, ifosfamide, imatinib, irinotecan, paclitaxel, vinblastine, vincristine, vinorelbine i effects W/ paroxetine,... [Pg.78]

Aprepitant (Emend) for prevention of nausea and vomiting due to cancer chemotherapy. Med Lett Drug Ther 2003 45 620. [Pg.394]

Aprepitant (Emend) Chlorpromazine (Thorazine) Dimenhydrinate (Dramamine, others) Dolasetron (Anzemet) Dronabinol (Marinol) Droperidol (Inapsine) Granisetron (Kytril)... [Pg.47]

Mid-Infrared Monitoring Applications during Development of the Vinyl Ether Formation Step in the Preparation of Aprepitant (Emend )... [Pg.349]

Five batches of the vinyl ether reaction were monitored by mid-lR using ReactlR MP (Mettler Toledo) during a pilot-plant campaign. Each batch yielded approximately 215 kg of vinyl ether for downstream production of aprepitant (Emend ) for phase 11 and 111 clinical trials. [Pg.353]

Aplysia dactylomela, 438 aprepitant [EMEND, 321 aryl trillates, 160 arylboronic acids, 146 AsPh , 153... [Pg.465]

Kolia et al. developed an efficient approach to produce enantiopure (35)-4-benzyl-3-(4-fluorophenyl)morphoIin-2-one (5)-(+)-5), a key intermediate of aprepitant (Emend Merck, Whitehouse Station, NJ), a NKl receptor antagonist... [Pg.1670]

See other pages where Aprepitant Emend is mentioned: [Pg.191]    [Pg.203]    [Pg.48]    [Pg.1334]    [Pg.568]    [Pg.434]    [Pg.275]    [Pg.277]    [Pg.279]    [Pg.281]    [Pg.283]    [Pg.285]    [Pg.287]    [Pg.289]    [Pg.367]    [Pg.636]    [Pg.672]    [Pg.229]    [Pg.1538]    [Pg.350]    [Pg.350]    [Pg.88]    [Pg.321]    [Pg.322]    [Pg.350]    [Pg.350]    [Pg.650]    [Pg.47]    [Pg.324]   
See also in sourсe #XX -- [ Pg.191 ]



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Aprepitant

Emend®

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