Approach Toward the Total Synthesis of Lundurines

The main tetracyclic core of these alkaloids has been synthesized via %-endo-dig cyclization of alkynyl indole catalyzed by AuCls, which affords exclusively the desired azocine[5,4—hjindole derivative (Scheme 1.41) [239]. Thus, based on previously reported results, our objective was to develop an efficient approach toward the total synthesis of lundurines. 

Scheme 4.77 Intermolecular approach toward the total synthesis of lundurines...

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