Applications of Flash Chemistry in Organic Synthesis

Flash Chemistry Fast Organic Synthesis in Microsystems Jun-ichi Yoshida 2008 John Wiley Sons, Ltd. ISBN 978-0-470-03586-3 

1 HIGHLY EXOTHERMIC REACTIONS THAT ARE DIEEICULT TO CONTROL IN MACROBATCH REACTORS 

---

In Chapter 4, we will discuss why flash chemistry is necessary. In Chapter 5, methods for the activation of molecules for flash chemistry will be discussed, because highly reactive species should be generated in order to accomplish flash chemistry. In Chapter 6, the problems associated with conducting extremely fast reactions and solutions to such problems will be discussed. In order to accomplish flash chemistry a device or a system for conducting an extremely fast reaction is crucial. In Chapter 7, we will briefly touch on state-of-the-art technologies of microflow systems, which are essential for flash chemistry. In subsequent chapters, some applications of flash chemistry in organic synthesis and polymer synthesis will be demonstrated. 

The main objective of this book is to provide, in a concise form, a current overall picture of flash chemistry background, principles, devices, and applications in organic and polymer synthesis. Because of space limitations our discussion in this book is not an exhaustive compilation of all known examples. Rather, it is a sampling of sufficient variety to illustrate the concept and the scope of flash chemistry. I usually focus on the works that have been done in my group as examples because I know them in more detail than other works reported in the literature. I hope that these examples and the accompanying discussions will serve as a guide to the potential of flash chemistry. 

---