Application on Reversible Kinetics

Solving the complete kinetic for the reaction t3 e (1.97) was always a task and the analytic solutions were formulated only in some special cases, for instance when =k (van Slyke Cullen, 1914). For general case of Eq. (1.97), although the condition for QSSA for the ES complex S5mthesis 

This work is devoted to furnish, for the first time, the complete elementary analytical solution for the progress reactant concentrations of the reversible enzymatic reaction (1.97). Such an approach may be found suited for treating the metabolic regulating mechanisms where regenerative, cyclical and thus necessarily reversible processes occur (Tzafriri Edelman, 2004). 

As earlier stated, though the employment of the QSSA condition (1.98) for the law of mass action on the equation (1.97), 

relation (1.100) can be further combined with the enz5miatic conservation. 

with relations (1.100) and (1.102) the instantaneous velocity of product formation can be calculated by means of the law of mass action of reaction (1.97), consecutively as  

---