Aporphines listing

Eximidine, Ci,Hj40N(0Me)3. (Item 36 list, p. 172.) A phenolic base, m.p. 133°, yielding a methiodide, m.p. 218° (dec.). It is isomeric with corydine and possibly belongs to the aporphine group (Manske). ... 

Berberine is probably the most widely distributed alkaloid. It and the allied alkaloids palmatine, jatrorrhizine, columbamine and coptisine occur somewhat frequently in the Rhcnadales (list, p. 169) as the tetrahydro-derivatives, but, in the botanical families referred to in the distribution list below, the tetrahydro-derivatives are exceptional and the unreduced alkaloids usual. The associated alkaloids include two members of the aporphine group, domesticine and t odomesticine (p. 315), one member of the cryptopine group, y-homochelidonine (p. 294) and two members of the double woquinoline type, viz., berbamine and oxyacanthine (p. 346). 

A useful and timely supplementary listing of new aporphines, oxoaporphines, phenanthrenes, and 4,5-dioxoaporphines has appeared.1 The alkaloids of Glaucium species, which include several aporphines and oxoaporphines, have been tabulated2 and a general discussion of the chemistry and biogenesis of isoquinoline alkaloids, including the aporphines, has been presented.3... 

The year under review has witnessed the isolation and structural elucidation of no less than nine new aporphines, as well as of five aporphine-benzylisoquinoline dimers. Two of these five aporphine-benzylisoquinolines, namely kalashine and khyberine, are the first such dimers known to be substituted at C-l 1 of the aporphine moiety. Thallium(m) trifluoroacetate is an oxidizing agent which effects the cyclization of tetrahydrobenzylisoquinolines to aporphines in satisfactory yields.1 A listing of aporphinoid alkaloids has appeared.2... 

Table 216-42 includes a listing of aporphines that have recently been re-isolated. 

In the search for new alkaloids, several known aporphines have been reisolated from the plant kingdom. The above listing of aporphines and the plants from which they have recently been reisolated (Table I, p. 17) represents an attempt to keep up with developments. 

The study of UV-spectra is a powerful tool for the structural elucidation of new aporphines (i, 61), and the spectral data in Table II are given as an addendum to the listings already recorded in the literature. 

A complete listing of all naturally occurring aporphines, oxoaporphines, and phenanthrenes is now available and a review on the applications of Pb(OAc)4 to the synthesis of several aporphinoids has appeared. ... 

Aporphines that have recently been reisolated, together with their natural sources, are listed below. 

A very useful complete listing of all proaporphine- and aporphine-benzyl-isoquinoline dimers, as well as aporphine-pavine dimers, together with their physical constants, has appeared. ... 

New aporphine alkaloids and their sources are shown in Table 1. Of particular interest in this listing are leucoxylonine and ocoxylonine, which are the first aporphines with only one unsubstituted aromatic carbon atom. ... 

For a complete listing of naturally occurring aporphines, with accompanying spectral data, see H. Guinaudeau, M. Leboeuf, and A. Cave, Lloydia, 38, 275 (1975). 

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