Antitumor royal jelly

Antitumor and antimetastatic actions by royal jelly in Leis lung... 

Antitumor and antimetastatic effects of royal jelly significantly did not differ at doses between 300 mg/kg and 600 mg/k of royal jelly. As shown in Fig. (3) , metastasis to the liver was caused by implantation of LLC cells. The area of metastatic tumors in the liver in royal jelly-treated mice was smaller than that in control mice Fig. (3) and Table (1) . 

This finding indicates that the antitumor and antimetastatic activities of royal jelly may be partly due to the direct inhibition of angiogenesis induced by solid tumors. This is the first report showing that royal jelly has an anti-angiogenic effect. 

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