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Antithrombosis and Anticoagulant Fluorinated Agents

Antithrombohtic eEects of razaxaban (an inhibitor of coagulation factor Xa) are currently being evaluated in Phase E trials. [Pg.324]

SSR-182289 is a direct thrombin inhibitor, stmcturally related to argotroban. It is undergoing Phase E clinical trials for thromboembohc disease treatment. [Pg.324]

Fluindione, ap-fluoro phenindione, is a vitamin K competitive antagonist used as an anticoagulant. The plasma haE-life of phenindione is strongly increased by the fluorine substitution (from 10 to 30 h). [Pg.324]


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And fluorination

Anticoagulant agents

Anticoagulants

Anticoagulation

Anticoagulation agents

Antithrombosis

Fluorinating agents

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