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Antisense oligonucleotides purification

State-of-the-art large-scale technologies for purification of therapeutic antisense oligonucleotides... [Pg.16]

Deshmukh, R. R., and Sanghvi, Y. S. (1997). Recent trends in large-scale purification of antisense oligonucleotides. IBC Con/. Large Scale oligonucleotide Synth., San Diego, CA, 1997. [Pg.474]

Purification of the oligonucleotides with the Nensorb-prep column will remove contaminating salts, failure sequences, and synthetic byproducts, which might interfere with the specificity of action of the antisense oligonucleotides (19)... [Pg.200]

Figure 12.3 Example chromatogram using the optimized siRNA reverse-phase denaturing HPLC purification protocol described here for the WAVE Oligo System (siRNA oligonucleotide Luciferase Antisense. n-Hexylammonium... Figure 12.3 Example chromatogram using the optimized siRNA reverse-phase denaturing HPLC purification protocol described here for the WAVE Oligo System (siRNA oligonucleotide Luciferase Antisense. n-Hexylammonium...

See other pages where Antisense oligonucleotides purification is mentioned: [Pg.189]    [Pg.16]    [Pg.379]    [Pg.405]    [Pg.405]    [Pg.511]    [Pg.512]    [Pg.519]    [Pg.519]    [Pg.519]    [Pg.530]    [Pg.531]    [Pg.531]    [Pg.106]    [Pg.1394]    [Pg.121]    [Pg.106]    [Pg.241]    [Pg.247]    [Pg.317]    [Pg.440]    [Pg.105]    [Pg.2]    [Pg.469]    [Pg.512]    [Pg.524]    [Pg.81]    [Pg.299]    [Pg.166]   
See also in sourсe #XX -- [ Pg.405 ]




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