Dopamine agonists Antipsychotics

Antipsychotics (conventional agents have nonspecific dopamine receptor antagonsim atypical agents also have serotonin antagonist activity), ecopipam, GBR-12909 and other partial dopamine agonists (may be functional antagonists)... 

Antihypertensives, diuretics, antipsychotics, tricyclic antidepressants, levodopa, dopamine agonists, a-blockers Corticosteroids NSAIDs, anticoagulants -Blockers (non-selective)... 

The hypothetical link between dopamine and schizophrenia was forged by two reciprocally related findings. The first was that potent dopamine agonist stimulants like d-amphetamine and cocaine could cause a psychosis that was schizophrenia-like, in that it had auditory hallucinations and paranoia. The second was that the neuroleptic drugs that were effective in reversing both schizophrenia and stimulant-induced psychosis were dopamine blockers. Moreover, the antipsychotic potency of the neuroleptics was proportional to their binding affinity to the D2 receptor. 

Chapter 2. Antipsychotic Agents and Dopamine Agonists John McDermed... 

Roger M. Finder, Organon International, Oss, The Netherlands Antipsychotic Agents and Dopamine Agonists 12... 

Some antipsychotics have dopamine antagonist actions, which wouid be expected to inhibit the efficacy of dopamine agonists such as bromocriptine. Carefui monitoring is required if combined use is considered necessary. 

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