Antimicrobial therapy antivirals

Eppstein, D. A., and Feigner, P. L. (1988). Applications of liposome formulations for antimicrobial/antiviral therapy, in Liposomes as Drug Carriers Recent Trends and Progress (G. Gregoriadis, ed.), John Wiley and Sons, Chichester, pp. 311-323. 

Their application in the biomedical field is clearly demonstrated by the preponderance of patents as compared to publications in the field. Calixarenes functionalized at the wide rim with sulfonic acid and sulfonamide groups showed anticoagulant and antithrombotic properties, approaching the activity of heparin and coumarin, currently used as anticoagulants in antithrombotic therapy. Calixarene derivatives are also active as antiviral, antimicrobial. and antifungal agents. 

The excellent improvement of this fever-responsive dysimmune neuropathy patient suggests that perhaps we should always treat dysimmune patients by combining anti-dysimmune and antiviral (or other antimicrobial) drugs, or one drug that does both. This concept is a putative model for future "combined anti-dysimmune plus anti-microbial therapy." And in each dysimmune patient we should always be searching for tracks of a relevant microbe."... 

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