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Antimicrobial pharmacodynamic properties

Drug-specific considerations in antimicrobial selection include the spectrum of activity, effects on nontargeted microbial flora, appropriate dose, pharmacokinetic and pharmacodynamic properties, adverse-effect and drug-interaction profile, and cost. [Pg.1019]

Integration of both pharmacokinetic and pharmacodynamic properties of an agent is important when choosing antimicrobial therapy to ensure efficacy and prevent resistance. Antibiotics may demonstrate concentration-dependent (aminoglycosides and fluoroquinolones) or time-depen-dent (/l-1 acta ms) bactericidal effects. [Pg.392]

Although not performed routinely during the clinical man- agement of patients with infections, data from certain laboratory tests (e.g., minimal bactericidal concentration tests, timed-kill tests, post-antibiotic-effect tests, and antimicrobial combination testing) are important for the clinician to understand because they help to determine an antimicrobial s pharmacodynamic properties. [Pg.1891]


See other pages where Antimicrobial pharmacodynamic properties is mentioned: [Pg.1027]    [Pg.245]    [Pg.524]    [Pg.1896]    [Pg.130]    [Pg.127]    [Pg.66]    [Pg.169]   
See also in sourсe #XX -- [ Pg.1027 , Pg.1038 ]




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Antimicrobial pharmacodynamics

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