Antimicrobial peptides circulation

The skin, together with the gastrointestinal and respiratory tracts, are the areas which are constantly exposed to microbes and, consequently, they are the main locations of synthesis of antimicrobial peptides. Besides their direct antimicrobial activity, antimicrobial peptides released from circulating cells or induced in the epithelia can also promote a response of the adaptive immune system. Different possible modes of action have been suggested for a- and / -defensins. It was suggested that antimicrobial peptides enhance the recruit-... 

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