Antimicrobial agents classification

Dallas P, Sharma VK, Zboril R. Silver polymeric nanocomposites as advanced antimicrobial agents classification, synthetic paths, applications, and perspectives. Adv Colloid Interface Sci 2011 166 119-35. http //dx.doi.Org/10.1016/j.cis.2011.05.008. 

P. Dallas, V.K. Sharma, and R. Zboril, Silver polymeric nanocomposites as advanced antimicrobial agents Classification, synthetic paths, apphcations, and perspectives, Adv. Colloid Interfac. Sci., 166,119-135,2011. 

Antimicrobial agents can be subdivided according to their mechanism of action, by their general structure or by their indications. For a systematic presentation of the various agents mostly some compromise between the three is found. In this text the structural relationships are the principal guidelines for their classification. 

Classification of some antimicrobial agents by their sites of action. 

Table 2.2 Classification of antimicrobial agents according to their dissociation constant (pKJ...

Table 2.3 Classification of antimicrobial agents as bactericidal or bacteriostatic...

The penicillins [pen i SILL in] are the most widely effective antibiotics and are among the least toxic drugs known the major adverse reaction to penicillins is hypersensitivity. The members of this family differ from one another in the R substituent attached to the 6-aminopenicillanic acid residue. The nature of this side chain affects their antimicrobial spectrum, stability to stomach acid, and susceptibility to bacterial degradative enzymes (P-lactamases). Figure 30.1 shows the main structural features of the penicillins. Figure 30.2 shows the classification of agents affecting cell wall synthesis. 

CAS 369-77-7 EINECS/ELINCS 206-724-5 Synonyms Carbanilide, 4,4 -dichloro-3-(trifluoromethyl)- N-(4-Chlorophenyl)-N -[4-chloro-3-(trifluoromethyl) phenyl] urea 4,4 -Dichloro-3-(trifluoromethyl)-carbanilide Trifluoromethyidichlorocarbanilide 3-(Trifluoromethyl)-4,4 -dichlorocarbanilide 3-Trifluoromethyl-4,4 -dichloro-N,N -diphenylurea Urea, N-(4-chlorophenyl)-N -[4-chloro-3-(trifluoromethyl) phenyl]-Classification Halogenated carbanilide Empin cal C14H9CI2F3N2O Formula CICF3C6H3HNCONHC6H4CI Properties M.w. 349.13 Uses Antimicrobial, deodorant agent in cosmetics Clonitralid... 

Classification Substituted phenol Empirical C8H8CI2O Properties M.w. 191.06 Uses Antimicrobial deodorant agent Manuf/Distrib. ABCR http //www.abcr.de Alfa Aesar http //www.alfa.com Lancaster Synthesis TCI Am. http //www.tciamerica.com Thomas Swan http //www.thomas-swan.co.uk... 

CAS 1341-08-8 14492-68-3 42566-92-7 EINECS/ELINCS 238-501-3 230635-5 Synonyms 1-[[(2-Hydroxyethyl) carbamoyl] methyl] pyridinium chloride, stearate 1-[2-Oxo-2-[[(1-oxooctadecyl) oxy] ethyl] amino] ethyl] pyridinium chloride Quaternium-7 N-(Stearoyl colamino formyl mefoyl) pyridinium chloride Classification Quaternary ammonium salt Ionic Nature Cationic Empirical C27H47N2O3 Cl Properties Wh. to It. cream powd. m.w. 483.21 Toxicology LD50 (IV, mouse) 56 mg/kg TSCA listed Uses Antimicrobial, antistat, emollient, emulsifier, foaming agent, cleanser, substantive agent, deodorant for cosmetics, toiletries, industrial applies. hair conditioner... 

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