Antifungal agents sodium propionate

Sodium propionate is also often used as an antifungal agent. Calcium is often preferable to sodium, both to reduce sodium levels in the diet and because calcium ions are necessary for the enzyme a-amylase to act on the starches in bread, making them available for the yeast, and improving the texture of the bread. Stale bread is caused by the starch amylose recrystallizing. The enzyme a-amylase converts some of this starch to sugars, which helps prevent recrystallization. 

Calcium propionate is often preferred as an antifungal agent, to reduce sodium levels in the diet, but also because calcium ions are necessary for the enzyme a-amylase to act on the starches in bread,... 

Therapeutically, sodium propionate has been used topically in concentrations up to 10% w/w alone or in combination with other propionates, caprylates, or other antifungal agents, in the form of ointments or solutions for the treatment of dermatophyte infections. Eye drops containing 5% w/v sodium propionate have also been used. See Section 18. 

In food processes, particularly baking, sodium propionate is used as an antifungal agent it may also be used as a flavoring agent in food products. In veterinary medicine, sodium propionate is used therapeutically as a glucogenic substance... 

Sodium Propionate, USP. Stxlium propionate occurs as transparent colorless crystals that are soluble in water and alcohol. It is an effeclivc antifungal agent that is u.sed as a preservative.. Sodium propionate is most effective at low pH. 

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