Older people anticholinergics

There is wide individual variation in the extent to which older people tolerate these drugs, and adverse effects, such as postural hypotension and anticholinergic effects, can be more problematic (586). Caution with neuroleptic drug use in old people is further warranted because several of these drugs are metabolized by CYP2D6, which is inhibited by many commonly used drugs (SEDA-20, 44). 

Anticholinergic effects Adverse effects that result from the suppressive action of certain mental health medications (antipsychotic and antidepressant medications) as well as other general medications (antihistamines). This affects the action of acetylcholine in the brain and peripheral nervous system. The actual side effects include dry mouth, blurred vision, constipation, and urinary hesitancy. This could present a particular problem when working with older people. 

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