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Antibody-targeted chemotherapy

Damle NK, Frost P. Antibody-targeted chemotherapy with immunoconjugates of calicheamicin. Curr Opin Pharmacol 20(B 3 386-90. [Pg.83]

Larson RA, Boogaerts M, Estey E, et al. Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg [gemtuzumab ozogamicin]. Leukemia 2002 16 1627-1636. [Pg.2328]

Sievers EL et al. Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy a phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood 1999 93 3678-3684. [Pg.355]

Green SK, Francia G, Isidore C et al (2004) Antiadhesive antibodies targeting E-cadherin sensitize multicellular tumor spheroids to chemotherapy in vitro. Mol Cancer Ther 3 149-159... [Pg.249]

In addition to monoclonal antibody or chemotherapy, immunotherapy has been developed to target tumor antigen for the treatment of FL. The unique sequence of the protein, so-called idiotype (Id) protein, can be a target of immunotherapy. Because Id protein can induce humoral and cellular immune responses against idiotype protein, vaccination with Id protein can decrease the risk of progression. However, the mechanism of anti-Id response has been unclear. [Pg.218]

Ferero-Torres A, Infante JR, Waterhouse D, Wong L, Vickers S, Arrowsmith E, et al. Phase 2, multicenter, open-label study of tigatuzumab (CS-1008), a humanized monoclonal antibody targeting death receptor 5, in combination with gemcitabine in chemotherapy-naive patients with unresectable or metastatic pancreatic cancer. Cancer Med 2013 2(6) 925-32. [Pg.590]


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See also in sourсe #XX -- [ Pg.385 ]




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Antibodies, targeting

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