Antibody diversity and B cell subsets

Extensive evidence for the distribution of the B cell population into subsets that differ in the expression of serologically defined cell surface markers has been presented (reviewed in [151]). Two major subsets that differentially express markers termed Lyb-3, Lyb-5 and Lyb-7 (abbreviated Lyb-5+ and Lyb5-5 B cells) exist in the mouse B cell population. More recently, a small subset of murine B cells that 

I would like to thank Malcolm Gefter, Larry Wysocki and Martin Weigert for many insightful discussions. This work was supported in part by a Grant from the National Institutes of Health, AI23739. 

32 Brodeur. P. and Riblet, R. (1984) in Regulation of the Immune System, pp. 444-453. Liss, New York. 

41 Kindt, T. and Capra, J.D. (1984) in The Antibody Enigma. Plenum Press. New York. 

58 Kelsoe, G. and Farina. D. (1986) in Evolution and Vertebrate Immunity The Antigen Receptor and MHC Gene Families, (G. Kelsoe and D. Schulze. Eds.). University of Texas Medical Branch Series on Biomedical Sciences. 

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