Drug resistance antibacterial agents

The second general mechanism to cause resistance to antibacterial agents is to prevent the drug from reaching its target site. This is either achieved by altered rates of entry (reduced uptake) or by the active removal of the dtug (active efflux) [4]. 

In its report ( 3) issued in 1972, the Task Force acknowledged the potential human and animal health hazard of drug resistant bacteria and made a number of recommendations. In addition to basic research to better understand the nature of the problem, the Task Force recommended that restrictions be placed on the use of antibacterial agents in feeds which fail to meet guidelines established by the Task Force in regard to safety and/or efficacy. Agents that do not meet these standards would be prohibited from growth promotion and any subtherapeutic use in animals but could continue to be used at therapeutic levels for short-term treatment on the order of licensed veterinarians. 

There are four general properties for a good antibacterial agent. It must be selective. Eliminating all species of bacteria from the body may leave the patient prone to superinfection. It should kill bacteria rather than just prevent their multiplication it should be bactericidal rather than bacteriostatic. Bacteria should not develop resistance to the drug. Lastly,... 

Antibacterials Soap and water are just as good as the antibacterial agents that create drug-resistant bacteria that are found in these cleansers and other cosmetic products. 

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