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Antibacterial agents antitubercular

Control of tuberculosis, long one of the scourges of mankind, began with the introduction of effective antibacterial agents. Thus, this disease was treated initially with some small measure of success with various sulfa drugs the advent of the antibiotic, streptomycin, provided a major advance in antitubercular therapy, as did the subsequent discovery of isoniazid and its analogs. [Pg.222]

Acnisal salicylic acid, aconiazide [inn] is an isoniazid analogue and an ANTITUBERCULAR and ANTIBACTERIAL AGENT, aconitine is an alkaloid from monk s hood or wolfsbane (Aconitum napellus) and other Aconltum spp. (Ranunculaceae). It is a NEUROTOXiN implicated in poisoning by A. spp., especially, 4. chasmanthum in India. Experimentally, it is a SODIUM-CHANNEL ACTIVATOR that binds to Na -channels, slows inactivation, shifts inactivation to a more negative value, and alters ion specificity. This results in repetitive firing of neurons, with marked effects on the heart including positive inotropism and arrhythmias. Aconitine (and the related alkaloid delphinine) were formerly used in... [Pg.4]

Joshi SD, Joshi A, Vagdevi HM, Vaidya VP, Gadaginamath GS (2010) Synthesis of some new quinolinylpyrazoles as potential antibacterial and antitubercular agents. Indian J Heterocycl Chem 19 221-224... [Pg.199]

In addition, various pyridopyridazines have been claimed to have activity as antibacterials and antiseptics, antitubercular agents, analgesics, anti-inflammatories, antiallergics, tranquillizers, CNS depressants and muscle relaxants. [Pg.261]

All sizes Variously intra-arterial, intravenous Antiasthmatics, analgesics, bronchodialators narcotics mucolytics antibacterials antituberculars hypoglycemics steroids antitumor agents amino acids... [Pg.552]

Hydrazides have also been used as nucleophiles for ring opening to give the corresponding bis(acylhydrazides) 540. ° Subsequent cyclodehydration of 540 leads to the 4-alkylidene(arylidene)imidazolones 541 that have been evaluated as anticonvulsant, antihelmintic, antibacterial, antifungal, antiviral, and antitubercular agents (Scheme... [Pg.246]

Spanish Fly cantharides. spantide I [DArg, oTrp -, Leu ] Pl-ll. sparfloxacin [ban. inn. usan] fluoroquinolone, is a broad-spectrum ANTIBACTERIAL which can be used as an ANTILEPROTIC and ANTITUBERCULAR AGENT. [Pg.260]

See other pages where Antibacterial agents antitubercular is mentioned: [Pg.368]    [Pg.368]    [Pg.14]    [Pg.61]    [Pg.115]    [Pg.215]    [Pg.219]    [Pg.600]    [Pg.625]    [Pg.243]    [Pg.445]    [Pg.625]    [Pg.375]    [Pg.157]    [Pg.238]    [Pg.262]    [Pg.291]    [Pg.134]    [Pg.445]    [Pg.357]    [Pg.79]    [Pg.193]    [Pg.134]    [Pg.329]    [Pg.368]   
See also in sourсe #XX -- [ Pg.192 , Pg.193 ]



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Antibacterial agent

Antitubercular

Antitubercular agents

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