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Antiamoebic agents

Sastry and Aruna described the use of 3-methyl-2-benzothiazolinone hydrazone hydrochloride as a new technique for the spectrophotometric determination of diloxanide furoate and other anthelmentic and antiamoebic agents [29]. Aliquots of sample solutions containing 10-100 pg of drug substance were transferred into a series of 10 mL graduated test tubes, and the volume adjusted to 3 mL with the respective solvent blank. 3-Methyl-2-benzothiazolinone hydrazone hydrochloride and 1 mL of Cr(VI) were added, and the mixture diluted with methanol. The absorbance at 500 nm was measured against a reagent blank. [Pg.274]

Diloxanide is used as the furoate ester, which is more effective as an antiamoebic agent than is diloxanide itself The ester is hydrolyzed in the intestine, and only diloxanide appears in the plasma from which it is... [Pg.278]

Five of 6 patients who failed to respond to other antiamoebic agents had complete resolution with 0.02% PHMB. Only PHMB was cysticidal at low concentrations (Larkin et al.). [Pg.216]

Amoeba infections have also been pointed out as etiologic agents in rheumatoid and other connective tissue diseases and organic antiamoebic agents, including copper salts have been used to successfully treat these diseases [563]. [Pg.524]

Uses This compound is used as an anti-infective agent antiamoebic agent intravaginal trichomonacide used to impregnate cotton bandages for antibacterial purposes in animals as an intestinal anti-infective agent. UCU A... [Pg.1204]

Ramtrez-Galicia G, Martmez-Pacheco H, Garduno-Juaiez R, Deeb O (2011) Exploring QSAR of antiamoebic agents of isolated natural products by MLR, ANN, and RTO. Med Chem Res 21 2501-2516... [Pg.3365]

Vanadium compounds containing thiosemicarbazide- and hydrazide-derived ligands, such as 26 and 27 in Figure 5.15, exhibit antiamoebic activity against Entamoeba histolytica. This water-borne amoebic protozoan parasitises the human intestines and in some cases other visceral organs, especially the liver. It is the aetiological agent of amoebiasis (also known as amoebic dysentery) and thus responsible for amoebic colitis and intestinal and liver abscesses. Symptomatic patients typically suffer from abdominal pain, diarrhoea... [Pg.179]

The most interesting of the varied types of triterpenes from the point of view of biological activity are the quassinoids. They exhibit antiamoebic (353), antimalar-ial (1020), antimitotic (287), antitumor (59, 403, 950), and cytotoxicity (59, 821, 823) effects. Bruceantin, 29, is being developed as a potential cancer chemotherapeutic agent and is currently in Phase 1 clinical trials in the United States (950). [Pg.1069]


See other pages where Antiamoebic agents is mentioned: [Pg.538]    [Pg.422]    [Pg.464]    [Pg.10]    [Pg.265]    [Pg.2173]    [Pg.4814]    [Pg.538]    [Pg.422]    [Pg.464]    [Pg.10]    [Pg.265]    [Pg.2173]    [Pg.4814]    [Pg.517]    [Pg.517]    [Pg.464]    [Pg.521]    [Pg.362]    [Pg.241]    [Pg.622]    [Pg.145]    [Pg.265]    [Pg.223]   


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