Antiadhesion layer

In the future we plan to clarify the role of adsorbed proteins and their influence on bacterial adhesion, involving studies with fibronectin which seems to play a key role in cellular adhesion processes. As the composition of the original polymer surface determines the nature of the adsorbed protein layer, it might be possible to modify the polymer surface in a way that proteins with antiadhesive properties are selectively adsorbed. Such an effect is known for albumin on platelet adhesion in a former study we could show that albumin is preferentially adsorbed onto radiation-modified hydrophilic surfaces. Bacterial adhesion to such surfaces is considerably reduced. 

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