Anti-solvent type supercritical

The anti-solvent type supercritical precipitation processes described earlier, e.g., GAS, are highly dependent on the solubility (or miscibility) between CO2 and solvent. In the case of CAN-BD, the particle size appears to be affected more by the CO2 to water ratio, and much less by the solubility of CO2 in the water. We plan to do further work in the future to substantiate the correlation shown in Figure 7 by vaiying other pertinent process parameters. 

At high pressures a considerable amount of a gas can be dissolved in a liquid solution. Once dissolved in the liquid phase it may act as an anti solvent. In literature this type of drowning out is often referred to as the Gas Anti-Solvent (GAS) process, it is also known as the Supercritical Anti-Solvent (SAS) process or as Precipitation with a Compressed fluid Anti solvent (PCA). 

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