Anti-obesity agent

Siuciak, JA, Clark, MS, Rind, HB, Whittemore, SR and Russo, AF (1998) BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain. J. Neurosci. Res. 52 149-158. Sprague, JE, Everman, SL and Nichols, DE (1998) An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine. Neuro toxicology 19 427-A42. Stock, MJ (1997) Sibutramine a review of the pharmacology of a novel anti-obesity agent. Int. J. Obesity 21 (Suppl 1) S25-S29. 

CoMFA/ CoMSIA Studies on Peripherally Acting CB1 Receptor Antagonists as Anti-Obesity Agents... 

There has been limited short-term experience as anti-obesity agents with the SSRI citalopram [101,102], and with the serotonin-noradrenaline reuptake inhibitor venlafaxine [103], and no recommendations can be made re use of these agents solely as anti-obesity therapy in clinical practice. 

Stock MJ (1997) Sibutramine a review of the pharmacology of a novel anti-obesity agent. Int J Obes Relat Metab Disord 21, Suppl 1 S25-S29... 

CgBrF 17 Contrast media Radiation-sensitizing agent Anti-obesity agent Oral liquid 423-55-2 Aug. 1 993/ Alliance Pharm... 

Conventional treatments for obesity have focused largely on strategies to control energy intake, however, the long-term efficacy of such approaches is hmited [12]. A reduction of dietary fat adsorption by an inhibitor of digestive Upases hold great promise as an anti-obesity agent. 

Interactions between NPY and the various other stimulatory and inhibitory transmitters known to be involved in the regulation of feeding will provide us with a better understanding of the neuronal pathways involved. Physiological inhibitors of feeding such as leptin or GLP-1 are possible targets for the development of novel anti-obesity agents. 

NPY as a powerful stimulator of feeding remains a potentially better target for the development of anti-obesity agents than inhibitors since the development of specific antagonists is favoured over the development of chemical mimics. 

Oo CY, Akbari B, Lee S, Nichols G, HeUmami CR. Effect of orlis a novel anti-obesity agent, on the pharmacokinetics and pl nnacotfynamics of pravastatin inpatients with mild hy-percholesterolaemia. Clin Drug Invest (1999) 17,217-23. 

Piperidinyloxy aryl sulfonamides New chemical class of selective 5-HT6 receptor antagonists as potential anti-obesity agents... 

Dried ripe ihiits of Ziziphus are used to tonify the spleen and stomach, moisten heart and lungs, nourish and pacify the spirit, smooA herbal action, and harmonize drugs. The roots have hypotensive effects, and the leaves can decrease the intake of sweets (as a taste-modifier and anti-obesity agent) (52). 

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