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Anti-addictive activity

Sweetnam P., Lancaster J., Snowman A. et al. Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine s putative anti-addictive activity. Psychopharmacology. 118 369, 1995. [Pg.106]

Another example is the indole alkaloid ibogaine. Radioligand binding assays revealed that ibogaine interacted with a wide variety of receptors at concns. of 1-100 p.M. These included the opiate, 5-HT2, 5HT3, and muscarinic [, 2 receptors, and the dopamine, norepinephrine, and serotonin uptake sites. Furthermore, ibogaine interacted with N-methyl-D-aspartic acid (NMDA) associated ion and sodium ion channels. This broad spectrum of activity may in part be responsible for ibogaine s putative anti-addictive activity [80]. [Pg.95]

V-gated Na+ channel, cr) [anti-addictive, anticonvulsant, CNS activity, hallucinogenic]... [Pg.203]

See other pages where Anti-addictive activity is mentioned: [Pg.62]    [Pg.62]    [Pg.912]    [Pg.96]    [Pg.163]    [Pg.38]    [Pg.219]    [Pg.119]    [Pg.451]    [Pg.912]    [Pg.755]    [Pg.784]    [Pg.15]    [Pg.225]    [Pg.814]    [Pg.984]    [Pg.755]    [Pg.784]    [Pg.1]    [Pg.1]    [Pg.9]    [Pg.46]    [Pg.85]    [Pg.86]    [Pg.93]    [Pg.119]    [Pg.225]    [Pg.124]    [Pg.70]    [Pg.114]    [Pg.331]    [Pg.335]    [Pg.382]    [Pg.115]    [Pg.113]    [Pg.17]    [Pg.386]    [Pg.613]    [Pg.356]    [Pg.231]    [Pg.16]    [Pg.531]    [Pg.447]   
See also in sourсe #XX -- [ Pg.21 , Pg.95 ]

See also in sourсe #XX -- [ Pg.95 ]



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Addiction

Addictive

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