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Antagonists sigma receptors

Remoxipride is a selective D2 antagonist with higher affinity for the D2S subtype of receptors. It has no affinity for 5-HT, adrenergic, muscarinic or histamine receptors but, unlike the other atypical neuroleptics, does bind to sigma receptors (see p. 453 for possible importance of sigma receptors). [Pg.272]

Javitt DC, Jotkowitz A, Sircar R, Zukin SR. 1987. Noncompetitive regulation of phencyclidine/sigma-receptors by the N-methyl-D-aspartate receptor antagonist D-(-)-2-amino-5-phosphonovaleric acid. Neurosci Lett... [Pg.81]

Sertraline also has mild antagonist actions at sigma receptors... [Pg.429]

Sigma receptor antagonists for reducing the motor side-effects of neuroleptics Antispasmodics, muscle relaxants Cytotoxic agents (high dose)... [Pg.315]

Pierce, R. C., and Rebec, G. V., 1992, Dopamine-, NMDA-, and sigma-receptor antagonists exert differential effects on basal and amphetamine-induced changes in neostriatal ascorbate and DOPAC in awake, behaving rats. Brain Res. 579 59-66. [Pg.309]

Iwamoto, E.T. Locomotor activity and antinociception after putative mu, kappa and sigma opioid receptor agonists in the rat Influence of dopaminergic agonists and antagonists. J Pharmacol Exp Ther 217 451-460, 1981. [Pg.24]

See other pages where Antagonists sigma receptors is mentioned: [Pg.14]    [Pg.76]    [Pg.142]    [Pg.142]    [Pg.60]    [Pg.60]    [Pg.1152]    [Pg.145]    [Pg.633]    [Pg.234]    [Pg.456]    [Pg.248]    [Pg.145]    [Pg.280]    [Pg.445]    [Pg.457]    [Pg.66]    [Pg.1931]    [Pg.208]    [Pg.240]    [Pg.693]    [Pg.49]    [Pg.271]    [Pg.219]    [Pg.313]    [Pg.319]    [Pg.320]    [Pg.142]    [Pg.143]    [Pg.145]    [Pg.146]    [Pg.74]    [Pg.227]    [Pg.69]    [Pg.219]    [Pg.542]    [Pg.74]    [Pg.338]    [Pg.447]    [Pg.258]   
See also in sourсe #XX -- [ Pg.456 ]



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Sigma

Sigma receptors

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