Annonaceae aporphinoids

Aporphinoids are by far the most abundant alkaloids in this genus and also, generally speaking, in the family Annonaceae. Guatteria has proved to be a rich source of unusual structures of this general type. Aporphines have been reviewed in Volume 24 of this treatise (3) and elsewhere (4-7), and a review on aporphinoids of the Annonaceae has just been published (8). For this reason we address the structures and chemistry of only a few alkaloids of this type that have not been included in the Kametani and Honda review (5). 

A number of structural types that have been found in Guatteria species and occasionally in other genera of the Annonaceae appear to be related biogenetically to the aporphinoids. The lack of experimental proof of this derivation, which is discussed in a later section (see Section V), makes it advisable to consider these compounds separately. 

More recently, eupolauridine has been isolated from Cananga odorata (Annonaceae). This alkaloid may be an aporphinoid, derived by a complex series of transformations from an aporphine oi a proaporphine precursor. ... 

First, the alkaloid composition of the Annonaceae is much more complex than was recognized a decade ago, when to an alkaloid chemist the name Annonaceae only meant aporphinoids and berberines. 

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