1,4-Anhydrosorbitol

Starting with 1,4-anhydrosorbitol 75 (prepared from D-glucitol) their synthesis proceeded in 19 steps (4% overall) via key intermediate 77. Intramolecular Claisen cyclization of 77 afforded 78 which was converted to the more advanced intermediate 79. 

When sorbitol is esterified the product is mainly a monoester (laurate, oleate, stearate) of 1,4-anhydrosorbitol. Mixed with other surfactants these are employed in cosmetics (suntan lotions, deodorants, skin creams, hair creams and sham-... 

In contrast, operating in the presence of palladium catalysts at 250°C under 80 bar hydrogen pressure cyclodehydration reactions of sorbitol and mannitol occurred with formation of cyclic ethers (isosorbide 5, 2,5-anhydromannitol, 2,5-anhydroiditol, and 1,4-anhydrosorbitol) (6), Up to 50% and 90% yield of isosorbide were obtained from sorbitol and mannitol, respectively. These... 

Anhydrosorbitol Esters. Eatty acid esters of anhydrosorbitol (see Alcohols,polyhydric) are the second largest class of carboxyHc ester surfactants. The important commercial products are the mono-, di-, and triesters of sorbitan and fatty acids (Table 18). Sorbitan is a mixture of anhydrosorbitols, principally 1,4-sorbitan (1) and isosorbide (2) ... 

Anhydrosorbitol esters are prepared commercially by direct esterification of sorbitol with a fatty acid at 225—250°C in the presence of an acidic... 

Ethoxylated Anhydrosorbitol Esters. Ethoxylation of sorbitan fatty acid esters leads to a series of more hydrophilic surfactants (Table 19). All hydroxyl groups of sorbitan can react with ethylene oxide. The stmcture of the principal component of a nominal polyoxyethylene (20) sorbitan monostearate illustrates the composition of these products, where w x y z = 20. 

The products of esterification of D-sorbitol by linseed fatty acids are excellent drying oils and these products are doubtless derivatives of anhydrosorbitol.92... 

METHACRYLIC ACID AND DERIVATIVES] (Vol 16) Ethoxylated anhydrosorbitol monolaurate [9005-64-5]... 

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