Androgen receptor protein

D. R. Rowley, D. J. TindaU (1986). Androgen receptor protein purification and molecular prop-... 

Moreover, DHT was shown to bind preferentially to specific nuclear (androgen) receptor proteins (Mainwaring, 1969 Fang et al.,... 

H14. Hobisch, A., Culig, Z., Radmayr, C., Bartsch, G., Klocker, H., and Hittmair, A., Distant metastasis from prostatic carcinoma express androgen receptor protein. Cancer Res. 55,3068-3072 (1995). 

Res 6-14 (VGGAWTGV) (Du et al. 2003 H.Y. Hu, personal communication) Androgen receptor protein Mutations leading to increase in polyglutamine stretches (Q11-35 noimal, Q40-62 pathological) (Katsuno et al. 2004)... 

FSH acts on testicular Sertoli cells to promote maturation of LH receptors and produce an androgen-binding protein. 

Anabolics are testosterone derivatives (e.g., clostebol, metenolone, nan-drolone, stanozolol) that are used in debilitated patients, and misused by athletes, because of their protein anabolic effect. They act via stimulation of androgen receptors and, thus, also display androgenic actions (e.g., virilization in females, suppression of spermatogenesis). 

Meyer, R., Wolf, S.S. and Obendorf M. (2007) PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor. The Journal of Steroid Biochemistry and Molecular Biology, 107, 1-14. 

Kahl, P., Gullotti, L., Heukamp, L.C., Wolf, S., Friedrichs, N., Vorreuther, R., Solleder, G., Bastian, P.J., Ellinger, J., Metzger, E., Schule, R. and Buettner, R. (2006) Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Research, 66, 11341-11347. 

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