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Analytical methods for povidone

Stability of the molecular weight in liquid dosage forms after sterilization with gamma radiation [Pg.37]

Unlike the powders, aqueous solutions of povidone are sensitive to gamma radiation. This was checked with povidone K 17 and povidone K 30. Table 29 presents the results of molecular weight measurements on povidone K17 that was exposed, as the 10% aqueous solution, to radiation of different intensities. A clear increase in the average molecular weight and a broadening of the molecular weight distribution were found. [Pg.37]

There are cases in which the molecular weight of the povidone grade used does not change, as it has been found that certain substances such as iodine or iodides can prevent this undesirable effect. Further, no increase in the molecular weight of a solution of povidone K 30 in a mixture of 90% polyethylene glycol and 10% water was observed after gamma irradiation. [Pg.37]

See other pages where Analytical methods for povidone is mentioned: [Pg.37]    [Pg.37]    [Pg.39]    [Pg.41]    [Pg.43]    [Pg.45]    [Pg.47]    [Pg.49]    [Pg.51]    [Pg.53]    [Pg.55]    [Pg.57]    [Pg.59]    [Pg.61]    [Pg.63]    [Pg.65]    [Pg.37]    [Pg.37]    [Pg.39]    [Pg.41]    [Pg.43]    [Pg.45]    [Pg.47]    [Pg.49]    [Pg.51]    [Pg.53]    [Pg.55]    [Pg.57]    [Pg.59]    [Pg.61]    [Pg.63]    [Pg.65]    [Pg.339]    [Pg.335]   


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Povidone

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