Beta blockers General anaesthetics

Information is fairly sparse, but these interactions appear normally to be of relatively minor importance. Be aware that changes in neuromuscular blockade (increases or decreases) can occur if beta blockers are used, but they seem to be unpredictable, and then often only modest in extent. The possible combined cardiac depressant effects of beta blockade and anaesthesia are well known (see Anaesthetics, general + Beta blockers, p.97). These effects may not be prevented when a neuromuscular blocker is used that has little or no effect on the vagus (such as atracurium or vecuronium). 

BETA-BLOCKERS ANAESTHETICS-GENERAL Risk of severe hypotensive episodes during induction of anaesthesia (including patients using timolol eye drops) Most general anaesthetics are myocardial depressants and vasodilators, so additive 1 BP may occur Monitor BP closely, especially during induction of anaesthesia... 

BACLOFEN, TIZANIDINE 1. ANAESTHETICS - general 2. ANTICANCER AND IMMUNOMODULATING DRUGS - IL-2 3. ANTIDEPRESSANTS - MAOIs 4. ANTI HYPERTENSIVES AND HEART FAILURE DRUGS 5. ANTI-PSYCHOTICS 6. ANXIOLYTICS AND HYPNOTICS 7. BETA-BLOCKERS 8. CALCIUM CHANNEL BLOCKERS 9. DIURETICS 10. NITRATES 11. PERIPHERAL VASODILATORS-moxisylyte (thymoxamine) 12. POTASSIUM CHANNEL ACTIVATORS t hypotensive effect Additive hypotensive effect. Tizanidine also has a negative chronotropic effect and may cause additive bradycardia with beta-blockers and calcium channel blockers Monitor BP at least weekly until stable. Warn patients to report symptoms of hypotension (light-headedness, dizziness on standing, etc.)... 

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