Anacyclus pyrethrum pellitorine from

Pellitorine (1) has been isolated from several plants fruits of Piper sarmentosum [7], roots of Anacyclus pyrethrum [8] and seeds of Piper sylvaticum and presents insecticidal activity [10]. The Z-isomer (2), isolated from Piper guineense [11], has similar activity. Another component of the dried fruits of Piper sarmentosum, known in Thailand as Cha-plu , is sarmentine (3) which is used as an expectorant [7]. The corresponding piperidine derivative (4) is an Achillea amide [12]. 

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