Amphipathic taurocholic acid

Simple micelles, composed only of bile salts, have a limited capacity to solubilize cholesterol. With taurocholate for example, one molecule of cholesterol is solubilized by 25 molecules of bile salt, while addition of a monoglyceride to the preparation essentially doubles the solubilization of cholesterol[17]. Obviously, the participation of additional amphipaths and amphiphiles, such as phospholipids and fatty acids, in the micellar structure causes dramatic increases in sterol solubility (from 100-1000 fold)[48]. 

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