AMPA receptor subunit mRNAs in the neocortex

For GluR-A-negative/GluR-B-positive cells, there were 58% in layers II and III, 61.5% in layer IV, 55.5% in V and 62% in VI (Kondo et al., 1997). In layers II, III, V and VI these GluR-A-negative/GluR-B-positive cells are mostly pyramidal in layer IV, they are both pyramidal and non-pyramidal (Kondo et al., 1997). These layer IV non-pyramidal cells may be a modified pyramidal cell type termed spiny stellate . 

AMPA RECEPTOR SUBUNIT mRNAs IN NEOCORTICAL INTERNEURONS 

The no or little GluR-B rule for GABAergic intemeurons is not absolute. GluR-A/GluR-B double-positive cells in layers II-VI are mainly bipolar or multipolar and have intense calbindin-D28K immunoreactivity (Kondo et al., 1997). Some of these cells may be the bipolar 

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Fig. II. AMPA receptor subunit mRNAs in the neocortex and caudate putamen of the adult rat (X-ray film, coronal sections). (A), GluR-A (S), GluR-B (C), GluR-C (D), GluR-D. cc, corpus callosum CPu, caudate putamen ctx, neocortex S, septum. Roman numeral indicates cortical layer. The arrows in D highlight the GluR-D expression in layer IV (Wisden and Seeburg, unpublished).

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