Ammonium persulfate-silica gel

Keywords oxime, hydrazone, deoximation, ammonium persulfate-silica gel, microwave irradiation, ketone, aldehyde... 

Neat oxime (1 mmol) or dissolved in dichloromethane (2-3 mL) is combined with silica gel (10 times, w/w) and the dry powder is mixed with ammonium persulfate (5 mmol) using a vortex mixer. The contents are irradiated at full power in an alumina bath inside a Kenmore microwave oven (2450 MHz, 800 W). After completion of the reaction (monitored by TLC) the product is extracted into dichloromethane (4x30 mL) and purified by column chromatography. In the case of aldehydes, the crude product is filtered through a small bed of neutral alumina with dichloromethane. 

Figure 7. front propagating in a solution of 1,6 hexanediol diacrylate (40%) and DMSO (60%) with ultrafine silica gel, 6.7% w/v. Ammonium persulfate was the thermal initiator and Irgacure 184 the photoinitiator. Courtesy of... 

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