Chlorpromazine Amitriptyline

Inducers of UGT include carbamazepine, phenobarbital, phenytoin and rifampin. Inhibitors of UGTs include amitriptyline, chlorpromazine, ciclosporin, clomipramine, diazepam, lorazepam, nitrazepam and valproic acid,... 

Simultaneous l-(2-pyrimidinyl)piperazine, metabolites, amitriptyline, chlorpromazine, clomipramine, duphenazine, imipreimine Noninterfering caffeine, diazepam, desipramine, mianserin, zimeldine Interfering haloperidol... 

Simultaneous amitriptyline, chlorpromazine, clomipramine, dothiepin, doxepin, fluoxetine, fluphenazine, haloperidol, imipramine, maprotiline, mianserin, norclomipramine, nordothiepin, nordoxepin, norfluoxetine, nortriptyline, paroxetine, remoxipride, sertraline, sulpride, thioridazine, trazodone... 

Extracted amitriptyline, chlorpromazine, desipramine, desmethyldoxepin, doxepin, imipramine, maprotiline, procainamide, propoxyphene, propranolol, thioridazine, trimipra-mine... 

Psychotropic drugs Amitriptyline, chlorpromazine, desipramine, doxepin, ffuphenazine, haloperidol, imipramine... 

Non-aqueous titration with acetous perchloric acid is used in the pharmacopoeial assays of adrenaline, metronidazole, codeine, chlorhexidine acetate, chlorpromazine.HCl, amitriptyline.HCl, propranolol.HCl, lignocaine.HCl and quaternary amine salts such as neostigmine bromide and pancuronium bromide. 

Figure 1.15 The Butterfly Angle . Tricyclic drugs consist of anticonvulsants (carbamazepine), antidepressants (amitriptyline), and antipsychotics (chlorpromazine). Although aU three families consist of three interconnected ring systems, the orientation between the rings varies, imparting a different spectrum of bioactivity.

Flavin monooxygenase (Ziegler s enzyme) H+ R3N R3N — R3N OH Chlorpromazine, amitriptyline, benzphetamine... 

Phenothiazines and related drugs, e.g., chlorpromazine (Largactil/ Thorazine). Some tricyclic antidepressants, e.g., amitriptyline Dibenzodiazepine derivatives and thienobenzodiazepines, e.g., clozapine, olanzapine Benzodiazepines, e.g., diazepam (Valium), nitrezepam (Librium) and lorazepam Barbiturates Opiates... 

Chlorpromazine Amitriptyline Loratadine Rupatadine Imipramine Azatadine Desloratadine... 

Molnar et al. [69] studied antibacterial effect and plasmid curing property of several phenothaizines and tried to correlate these functions with respect to their chemical structure. They observed that diethazine, amitriptyline, and impipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulfoxide and fluorescein were ineffective even at 1000 Ag/ml. The antibacterial compounds deleted at 40-70% frequency the F lac-t- plasmid of Escherichia coli K12 Le-140. Similar plasmid elimination potentiality by phenothiazines was reported by the same group of authors in 1982 [72],... 

Drugs that are known to be substrates of P-gp include antihistamines (e.g. terfenadine), digoxin, ciclosporin, hydrocortisone and other steroids and drugs used in chemotherapy (e.g. paclitaxel, vinblastine). Ciclosporin, in addition to being a substrate of P-gp, is also an inhibitor of P-gp. Drugs known to induce P-gp include morphine, dexamethasone, phenobarbital, rifampin and St John s wort. Inhibitors of P-gp include amiodarone, amitriptyline, atorvastatin, chlorpromazine, ciclosporin, erythromycin, fluphenazine, haloperidol, quinidine, ritonavir and verapamil,... 

Pinto J, Huang YP, and Riviin RS (1981) Inhibition of riboflavin metabolism in rat tissues by chlorpromazine, imipramine, and amitriptyline. Journal of Clinical Investigation 67,1500-6. 

Drugs that meet one or more of the criteria given above and have been shown to exhibit significant differences in the bioavailability of marketed dosage forms include digoxin, quinidine, furosemide, nitrofurantoin, prednisone, chloramphenicol, theophylline, chlorpromazine, phenytoin, amitriptyline, and phenylbutazone. 

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