3- Aminopropyl alcohol

Of the fourth pair, ergoraetrine was found by Jacobs and Craig to yield lysergic acid and cZ- -arainopropyl alcohol (Z-(-l-)- -aminopropyl alcohol), and the same products were obtained by Smith and Timmis 1 from its isomeride, ergometrinine. This pair of alkaloids mxist therefore be hydroxywopropylamides of lysergic acid. The first member of each... 

These hydrazides on treatment with nitrous acid are converted into azides, which with appropriate amino-alcohols, furnish ergometrine and its isomerides and analogues. The four pairs of stereoisomeric ergo-metrines and ergometrinines in the following list have been prepared in this way with l-( -(-)-)S-aminopropyl alcohol or its d-( —)-isomeride. 

The propanolamine obtained by hydrolysis of ergometrine and ergometrinine is dextrorotatory, but belongs to the I- series and appears to be fully described as Z-(-)-)- 3-aminopropyl alcohol. 

Aminopropanols or Aminopropyl Alcohols (Aminohydroxypropanes or Hydroxyaminopro-panes), CsH6(NHa)OH, mw 75.11, N 18.65%-Three isomers are described in Beil 4,288, 289,(432,433,437) [733,734,736]. Their picrates are listed under Picric Acid... 

SYNS P-ALANINOL Y-AMINOPROPAN OL 3-AMINOPROPANOL 3-AMINO-l-PROPANOL 3-AMINOPROPYL ALCOHOL 3-HYDROXYPROPYL-AMINE PROPANOLAMINE 1,3-PROPANOLAMINE... 

AMINOPROPYL ALCOHOL see PMM250 N-(2-(3-AMINOPROPYLAi ONO)ETHYL)-l,3-PROPANEDIAMINE see TBI700 N-(3-AMINOPROPYL)-N -(3-((3-AMINOPROPYL)AMINO)PROPYL)-l,3-PROPANEDIAMINE see TED600 (N-(3-AMINOPROPYL)-3-... 

Amino-l-phenylbutan-l-ol [a (a-aminopropyl)benzyl alcohol] [( )-threo 5897-76-7] M 165.1, m 79-80 , pK jt -9.7. Crystd from benzene/pet ether. 

The following is an alternative method of preparation 1 gram 2-(7-chloropropyl)-s-tri-azolo-[4,3-al-pyridine-3-one and 5 ml saturated ammonia alcoholic solution are heated for 5 hours in a closed tube at 100°C. The contents of the tube are cooled, the ammonium chloride filtered out and the solvent is removed. There remains a residue of 0.9 grams 2-(7-aminopropyl)-s-triazolo-[4,3-al -pyridine-3-one. 

Isolation of the diesters and hydroxyesters/alcohols fraction by anion exchange chromatography with an aminopropyl cartridge from a solution of 1 mg ml-1 of raw beeswax in CHCU/MeOH (2 1, v/v)... 

Cope and Burrows414 have prepared a number of aminoalkylbenzo-[6]thiophenes with the general formula (195) by Friedel-Crafts reaction between benzo[6]thiophene and various amino tertiary alcohols. On treatment with formamide in formic acid, (3-benzo[6]-thienyl)acetone affords 3-(2-aminopropyl)benzo[6]thiophene [Eq. (11)].557 Recent patents535,570 describe how isocyanates with the... 

Data for the use of alcohols as alkylating agents in superacids are scarce. A study of the alkylation of phenol and naphthols with ferf-butyl alcohol has shown198 that triflic acid adsorbed on aminopropyl-modified silica is the most selective to yield monoalkylated products compared to solid acids (triflates immobilized in silica). 

Many of the chiral molecules containing amide groups were bonded to a solid support for the preparation of CSPs [16-19]. The racemic compounds resolved on these CSPs include a-hydroxycarbonyls, /i-hydroxycarbonyls, amino acids, amino alcohols, amine, and derivatized and underivatized diols. The preliminary chiral diamide phase [(/V-foriuyl-L-valyl)aminopropyl)silica gel] has sufficient separability for racemic /Y-acylatcd a-amino acid esters but not in other types of enantiomer [16]. Most of the eluents used with these CSPs are of normal phase mode, including w-hcxanc, 2-propanol, chlorinated organic solvents, and acetonitrile. 

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