1 - -4-aminobutan

Chemical Designations - Synonyms 1-Aminobutane Butylamine Mono-n-butylamine Norvalamine Chemical Formula CH3(CHj)3NH4. 

The maximum recommended operating pressure is 1,450 psig (10 bar, lOMpa) to avoid charring caused by breakdown products of pyridazine and 4-aminobutanal. 

See related ALKYLMETALS, ALKYLSILANES j1723. Butylamine (1-Aminobutane)... 

Dao et al.36 have shown that for racemic S(+)-2-aminobutane-gossy-polone-imine lowering temperature to 280 K has slowed the interconversion of the diastereomers. 

Formation of the adduct with dirhodium complex [6] has significantly changed the chemical shift of the compounds in which proton transfer occurred, for example, for the adduct of iV-(5-nitrosalicylidene)-2-ami nobutane, the chemical shift was —198.2, which was shielded by of 110 ppm in comparison to that in the starting Schiff base.12 The large signal shift was due to the shift of the proton transfer equilibrium towards NH tautomer. For the adduct of N-(salicylidene)-2-aminobutane, existing in the OH-form, the 15N chemical shift has changed from —87.5 to — 84.6 ppm. 

The position of the proton transfer equilibrium for the Schiff bases being derivatives of rac-2-aminobutane [24] or rac-a-methylbenzylamine [25] and their adducts with dirhodium complex has been estimated in CDCI3 solution on the basis of measurements of deuterium isotope effects on 15N chemical shift.12 It was shown that adduct formation significantly influenced the position of the equilibrium which was manifested by AN(D) values. 

Aminobenzenethiol, a297 Aminobenzyl cyanide, a255 1-Aminobutane, b509... 

Ethambutol Hydrochloride (+)-2-Amino- Butan-l-ol TLC-Method Adsorbent-Silica Gel-G, Mobile Phase-Ethyl acetate Glacial acetic Acid HC1 H20(11 7 1 1) Apply 2pi of each of two solns. in MeOH, containing (1) 5% w/v of T.S. (2)0.050% w/v of (+)-2-aminobutan-l-ol. Remove TLC plates, dry in air, heat at 105°C for 5 mts, cool, spray with cadmium and Ninhydrin soln.2, heat to 90°C for 5 mts. The spot obtained with (2) is more intense than with (1). NMT 1.0... 

SCHEME 1. Conformational map of the RcRn and RcSn diastereomers of /V-ethyl-iV-methyl-2-aminobutane (EMAB). Interconversions among conformers within dashed boxes are fast on the NMR time scale at 104 K. Those between dashed boxes occur via rotations about the methine carbon-nitrogen bond with barriers which are DNMR-visible. The interconversion between the solid boxes occurs via nitrogen inversion (disstereomeric interconversion). The values in parentheses are MM2-80 results. Reprinted with permission from Reference 71. Copyright (1988) American Chemical Society... 

Fermenting baker s yeast transformed 2-butanone oxime containing 44% excess of the ( )-isomer into optically active (R)-2-aminobutane in 58% enantiomeric excess. The chiral amine was also obtained in 24% e.e. from the oxime acetate but the oxime methyl ether gave a racemic product (equation 2)16. 

Very recently (51), nonequivalence has been found in a variety of additional monobasic solutes whose configurational analysis was thought earlier to lie outside the scope of the CSA technique. 2-Butanol, for example, when dissolved in benzene saturated with TFAE, shows nonequivalence in both methyl resonances. A variety of other chiral and prochiral compounds such as 2-propanol, methyl 2-propyl sulfide, 2-aminobutane, and 2-methyl-1-butanol show nonequivalence for their enantiotopic methyl groups under these conditions. The magnitudes of nonequivalence in these instances are small (0.02-0.03 ppm) but, as illustrated in Figure 4 for enriched 2-butanol,... 

Abstract Titration of weak bases in non-aqueous solvents can provide valuable information about these weak bases. Some primary amines 1-aminobutane, 1-aminopropane, 2-aminoheptane, aminocyclohexane, 3-amino-l-phenylbutane were titrated with hydrochloric acid in toluene solvent. All the primary amines gave very well-shaped potentiometric titration curves. The same titrations were done with hydrochloric acid in methanol solvent to show the effect of amphiprotic solvent in the titrations with hydrochloric acid. 

Synonyms AI3-24197 1-Aminobutane BRN 0605269 Butan-l-amine 1-Butanamine n-Butylamine CCRIS 4756 EINECS-203-699-2 FEMA No. 3130 Monobutylamine Mono-/3-but-ylamine Norralamine Norvalamine NSC 8029 Tutane UN 1125. 

Amarthol fast orange R base, see 3-Nitroaniline Amatin, see Hexachlorobenzene Ameisenatod, see Lindane Ameisenmittel merck, see Lindane American Cyanamid 3422, see Parathion American Cyanamid 4049, see Malathion Amerstat 274, see Ethylenediamine Amfol, see Ammonia Amidox, see 2,4-D Amine 2,4,5-T for rice, see 2,4,5-T Aminic acid, see Formic acid 2-Aminoacetylfluorene, see 2-Acetylaminofluorene 4-Aminoaniline, see / Phenylenediamine p-Aminoaniline, see / Phenylenediamine 2-Aminoanisole, see oAnisidine 4-Aminoanisole, see p-Anisidine oAminoanisole, see oAnisidine joAminoanisole, see p-Anisidine Aminobenzene, see Aniline p-Aminobiphenyl, see 4-Aminobiphenyl 1-Aminobutane, see Butylamine l-Amino-4-chloroaniline, see 4-Chloroaniline l-Amino-4-chlorobenzene, see 4-Chloroaniline 1-Amino-p-chlorobenzene, see 4-Chloroaniline 4-Aminochlorobenzene, see 4-Chloroaniline p-Aminochlorobenzene, see 4-Chloroaniline 4-Aminodiphenyl, see 4-Aminobiphenyl... 

The Mannich reaction is best discussed via an example. A mixture of dimethylamine, formaldehyde and acetone under mild acidic conditions gives N,N-dimethyl-4-aminobutan-2-one. This is a two-stage process, beginning with the formation of an iminium cation from the amine and the more reactive of the two carbonyl compounds, in this case the aldehyde. This iminium cation then acts as the electrophile for addition of the nucleophile acetone. Now it would be nice if we could use the enolate anion as the nucleophile, as in the other reactions we have looked at, but under the mild acidic conditions we cannot have an anion, and the nucleophile must be portrayed as the enol tautomer of acetone. The addition is then unspectacular, and, after loss of a proton from the carbonyl, we are left with the product. 

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