1-Aminoadamantane hydrochloride

Chemical Name 1-adamantanamine hydrochloride Common Name 1-aminoadamantane hydrochloride Structural Formula nh ... 

The release characteristics of the L, Qn, and Hu LLC phases of GMO and water have been studied for the controlled release of large numbers of drug molecules. These drugs include common analgesics (aspirin [129,130]) vitamins (vitamin E [133]) antiviral drugs (1-aminoadamantane hydrochloride [132], acyclovir [134]) anionic drugs (sodium diclofenac [133, 135]) met-... 

Aminoadamantane hydrochloride Adamantanamine hydrochloride CioHisCIN 666-66-7 187.710 cry (al-eth) 360 dec vs HgO, EtOH... 

Aminoacetonitrile Aminoacetonitrile monohydrochloride a-Aminoacetophenone hydrochloride 1-Aminoadamantane hydrochloride... 

Amanatdine and Rimantadine are the 1-aminoadamantane hydrochloride and its a-methyl derivative. Both compounds are cyclic amines that inhibit the uncoating of the influenza A viral RNA within the infected host cell and hence prevent its replication. They are effective in prevention and treatment of influenza A infection in high risk individuals [13]. 

The second of these compounds was claimed to be comparable in activity to 1-aminoadamantane hydrochloride. Three amidines (LII-LIV) considered to be equivalent or superior to 1-aminoadamantane were found as a result of screening 280 amidine containing compounds against influenza in mice. 

Syntheses of the formamidine AdNHCH=NAd from 1-aminoadamantane hydrochloride (AdNH2,HCl) by reaction with s-triazene in pyridine and of the amide from p-(2-furyl)acrylie acid chloride and AdNH2 have been recorded the amide has antiviral activityReaction of 3-methylpentadienyl anion with adamantanone affords (668 75%) as the exclusive product the anion is a convenient reagent for the introduction of a 1,3-diene unit of the above type, and applications to terpene synthesis are discussed." Thermolyses of esters of P-hydroxyalkyltrimethylsilanes,... 

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