Amine groups secondary

Fluorescamine 10 ng Primary amine groups, secondary amines at high concentration, TRIS, ammonium sulfate (Phosphate does not interfere)... 

Desipramine [50-47-5] (35) and nortriptyline [72-69-5] (36) are demethylated derivatives and principal metaboHtes of (32) and (33), respectively. Both compounds possess less sedative and stronger psychomotor effects than the tertiary amine counterparts, probably because tricycHcs containing secondary amine groups generally show greater selectivity for inhibiting the reuptake of norepinephrine compared with the reuptake of serotonin. Protriptyline [438-60-8] (37), a stmctural isomer of nortriptyline, is another important secondary amine that displays a similar clinical profile. 

Fabric Softeners, Surfactants and Bleach Activators. Mono- and bisamidoamines and their imidazoline counterparts are formed by the condensation reaction of one or two moles of a monobasic fatty acid (typically stearic or oleic) or their methyl esters with one mole of a polyamine. Imidazoline formation requires that the ethyleneamine have at least one segment in which a secondary amine group Hes adjacent to a primary amine group. These amidoamines and imidazolines form the basis for a wide range of fabric softeners, surfactants, and emulsifiers. Commonly used amines are DETA, TETA, and DMAPA, although most of the polyethylene and polypropane polyamines can be used. 

Reactive Polyamide Resins. Another significant commercial appHcation of dimer acids is in reactive polyamide resins. These are formed by the reaction of dimer acids with polyamines such as diethylenetriamine to form polyamides containing reactive secondary amine groups (see DiAMlNES AND HIGHER AMINES, aliphatic). In contrast to nonreactive polyamides, these materials are generally Hquids at 25°C. 

Weakly basic anion resins derive their functionality from primary (R-NH), secondary (R-NHR ), tertiary (R-N-R 2), and sometimes quaternary amine groups. The weakly basic resin readily absorbs such free mineral acids as hydrochloric and sulfuric, and the reactions may be represented according to the following ... 

Compound 74 belongs to a special group which forms cyclic aldehyde ammonia 75 (cotarnine) by interaction of the secondary amine group with the aldehyde group. This aldehyde ammonia can be considered to be a pseudo base. 

Enamines derived from aldehydes can usually be obtained by the reaction of 2 equivalents of a secondary amine with the carbonyl compound, in the presence of anhydrous potassium carbonate, followed by pyrolytic distillation of the aminal with elimination of one of the amine groups (10,15, 30-36). Ketones are directly converted to enamines under the conditions of aminal formation. The azeotropic removal of water with excess aldehyde has also been described (32,37). 

Cross-linking of the polymer by secondary amine groups is not irreversible since these groups are easily destroyed when the polymer is treated with slightly alkaline solutions ... 

Schiffbase, 1147 Scurvy vitamin C and, 772 sec-Butyl group, 84 Second-order reaction, 363 Secondary alcohol, 600 Secondary amine, 917 Secondary carbon, 84 Secondary hydrogen. 85 Secondary structure (protein), 1038-1039... 

Primary amines with a-methyl groups Secondary amines unbranched on the a-carbon Tertiary amides... 

Adducts of a fatty amine adduct to unsaturated acid in which the product contains only secondary or tertiary amine groups that have a lower toxicity to the environment [391]. 

Epoxyfunctional siloxanes are also useful as softeners. These may be derived from polysiloxane (10.231) or from aminopolysiloxanes (10.232). Further possibilities are represented by the polyalkoxylated epoxyfunctional silicones (10.233) and polyalkoxylated aminofunctional silicones (10.234). However, it has been pointed out [485] that the reaction of epichlorohydrin with aminopolysiloxanes is not very specific, since primary and secondary amine groups are usually randomly epoxidised resulting in viscous products that... 

Reductive Amination to Secondary Amine Linkage with Terminal Formyl Group... 

It is obvious that the Mannich reaction pathway and the immonium ion mechanism may occur simultaneously, especially at conditions of room temperature or greater. Formaldehyde-facilitated crosslinking reactions between molecules that both contain nucleophiles probably occur primarily by the immonium ion pathway, since the Mannich reaction proceeds at a slower rate. In addition, the Mannich reaction will cause nondescript polymerization between molecules that possess both active hydrogens and amine groups. It is best to utilize the Mannich reaction only when one of the molecules contains no nucleophilic groups but at least one active hydrogen, and the other molecule contains a primary or secondary amine. 

Figure 7.11 Oxidation of glycoproteins with periodate, such as glycosylated antibodies, results in the formation of aldehyde groups that can be used for conjugation to dendrimers containing amine groups. Reductive amination with sodium cyanoborohydride results in coupling via secondary (or tertiary) amine bonds.

Primary amine-containing polymeric particles are available from a number of manufacturers and have either aliphatic or aryl amine groups on their surface. Occasionally, a particle type may have secondary or tertiary amines present, but these should be avoided for covalent coupling, as primary amines typically give better reaction yields than secondary amines and tertiary amines are unreactive. 

To create the free secondary amine group (N-H) fulleropyrrolidine, an amine-protected starting material can be used in the reaction (Cai et al., 2006). For instance, a trityl-oxazolidinone (using either triphenylmethyl- or better, 4-methoxytriphenylmethyl-protecting groups) can be reacted with C60 to yield the trityl-protected pyrrolidine (Figure 15.5). 

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